Tug of war at the exit door.

The lipid sphingosine-1-phosphate has been identified as a key exit signal for lymph nodes. In this issue of Immunity, Pham et al. (2008) show that its action can only be understood in the context of retention signals transduced by CCR7.

Détails bibliographiques
Auteurs principaux: Dustin, M, Chakraborty, A
Format: Journal article
Langue:English
Publié: 2008
Description
Résumé:The lipid sphingosine-1-phosphate has been identified as a key exit signal for lymph nodes. In this issue of Immunity, Pham et al. (2008) show that its action can only be understood in the context of retention signals transduced by CCR7.