Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide

B. pseudomallei is a gram-negative bacterium that causes the tropical infection melioidosis. In northeast Thailand, mortality from melioidosis approaches 40%. As exemplified by the lipopolysaccharide-Toll-like receptor 4 interaction, innate immune responses to invading bacteria are precipitated by a...

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Bibliographic Details
Main Authors: Chantratita, N, Tandhavanant, S, Myers, N, Seal, S, Arayawichanont, A, Kliangsa-Ad, A, Hittle, L, Ernst, R, Emond, M, Wurfel, M, Day, N, Peacock, S, West, T
Format: Journal article
Language:English
Published: Public Library of Science 2013

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