Target engagement: shining a light
The ability to measure the binding of a compound to its intended target in live cells or tissue is a critical parameter for drug discovery. A new method using polarized light microscopy adds to the current toolbox by enabling monitoring of target engagement in vitro and in vivo at single-cell resolu...
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| Format: | Journal article |
| Language: | English |
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Springer Nature
2017
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| _version_ | 1797086201321095168 |
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| author | Huber, K |
| author_facet | Huber, K |
| author_sort | Huber, K |
| collection | OXFORD |
| description | The ability to measure the binding of a compound to its intended target in live cells or tissue is a critical parameter for drug discovery. A new method using polarized light microscopy adds to the current toolbox by enabling monitoring of target engagement in vitro and in vivo at single-cell resolution. |
| first_indexed | 2024-03-07T02:18:43Z |
| format | Journal article |
| id | oxford-uuid:a32c81e6-5cd5-4f86-96a4-c5401260a259 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:18:43Z |
| publishDate | 2017 |
| publisher | Springer Nature |
| record_format | dspace |
| spelling | oxford-uuid:a32c81e6-5cd5-4f86-96a4-c5401260a2592022-03-27T02:24:58ZTarget engagement: shining a lightJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a32c81e6-5cd5-4f86-96a4-c5401260a259EnglishSymplectic Elements at OxfordSpringer Nature2017Huber, KThe ability to measure the binding of a compound to its intended target in live cells or tissue is a critical parameter for drug discovery. A new method using polarized light microscopy adds to the current toolbox by enabling monitoring of target engagement in vitro and in vivo at single-cell resolution. |
| spellingShingle | Huber, K Target engagement: shining a light |
| title | Target engagement: shining a light |
| title_full | Target engagement: shining a light |
| title_fullStr | Target engagement: shining a light |
| title_full_unstemmed | Target engagement: shining a light |
| title_short | Target engagement: shining a light |
| title_sort | target engagement shining a light |
| work_keys_str_mv | AT huberk targetengagementshiningalight |