Regulation of stemness and differentiation in colorectal cancer

Regulation of stemness and differentiation in colorectal cancer

The cancer stem cell (CSC) model of carcinogenesis and progression posits that within a tumor lies a subpopulation of cells that solely possess the ability to initiate a tumor and to differentiate into tumor cell lineages. Although the behavior of such cells is known, the challenge is to identify fa...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Gandhi, S
अन्य लेखक:	Bodmer, W
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2010
विषय:	Tumour pathology Stem cells (clinical sciences) Tumours Medical Sciences Gastroenterology Oncology

समान संसाधन

The role of ATF4 in hypoxia-induced cell death in cancer
द्वारा: Pike, L, और अन्य
प्रकाशित: (2011)

Mitochondrial modulators of hypoxia-related pathways in tumours
द्वारा: Snell, CE
प्रकाशित: (2013)

Characterising the role of circulating immune cells in brain metastasis
द्वारा: Balathasan, L
प्रकाशित: (2012)

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
द्वारा: Knowles, H, और अन्य
प्रकाशित: (2008)

MiR-215 regulates differentiation in colorectal cancer stem cells
द्वारा: Jones, M
प्रकाशित: (2014)

The use of novel xenografting methods to reveal differential gene expression between breast cancer at primary and metastatic sites
द्वारा: de Sousa, E, और अन्य
प्रकाशित: (2012)

The role of HER4 in relation to trastuzumab resistance and prognosis in HER2 positive breast cancer
द्वारा: Mohd Nafi, SN
प्रकाशित: (2014)

Functional analysis of cancer/testis antigens in human cancer
द्वारा: Pagotto, A
प्रकाशित: (2013)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
द्वारा: Ledaki, I
प्रकाशित: (2013)

Investigating a role of ASPP2 in the cellular response to infection
द्वारा: Lim, Y, और अन्य
प्रकाशित: (2014)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
द्वारा: Rao, SR
प्रकाशित: (2014)

The role of host microenvironment in the pathogenesis of multiple myeloma
द्वारा: Lwin, STS
प्रकाशित: (2014)

Angiogenesis in human lung tumours
द्वारा: Ferguson, ML
प्रकाशित: (2008)

Combining regulatory angiogenic gene therapy and virotherapy for the treatment of breast cancer
द्वारा: Bazan Peregrino, M
प्रकाशित: (2007)

Tumour-stroma interaction in pancreatic cancer
द्वारा: Lunardi, S
प्रकाशित: (2013)

Investigating the role of iASPP and ASPP2 in human carcinoma
द्वारा: Salter, V
प्रकाशित: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
द्वारा: Albukhari, A
प्रकाशित: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
द्वारा: Albukhari, A
प्रकाशित: (2014)

HR23B, a biomarker for HDAC inhibitors
द्वारा: Khan, OA
प्रकाशित: (2013)

Impact of TMPRSS2-ERG fusion gene on prostate cancer cell response to chemotherapy, radiotherapy and androgen deprivation therapy
द्वारा: Ovtcharov, S
प्रकाशित: (2015)

Modulating the immune system by amino acid depletion - IDO and beyond
द्वारा: Vallius, L
प्रकाशित: (2011)

Improving intraperitoneal adenovirus virotherapy for ovarian cancer
द्वारा: Thoma, CMM
प्रकाशित: (2011)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
द्वारा: Harjes, U
प्रकाशित: (2014)

The role of p53 in hypoxia-induced apoptosis
द्वारा: Poole, R
प्रकाशित: (2010)

Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
द्वारा: Potter, M
प्रकाशित: (2014)

CEA-targeted monoclonal antibody therapy in colorectal cancer
द्वारा: Conaghan, P, और अन्य
प्रकाशित: (2009)

The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
द्वारा: Jackson, M
प्रकाशित: (2013)

Loss of chaperone protein in human cancer
द्वारा: Adighibe, O
प्रकाशित: (2012)

Development of sindbis virus as an oncolytic agent
द्वारा: Kueberuwa, GLB
प्रकाशित: (2012)

Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/neu in breast cancer and is an independent predictor of prognosis
द्वारा: Winters, Z, और अन्य
प्रकाशित: (2003)

The influence of BRCA1's ubiquitin ligase activity on cell motility
द्वारा: Sengupta, S
प्रकाशित: (2014)

Cancer stem cells - the current status of an old concept: literature review and clinical approaches
द्वारा: Lukasz Fulawka, और अन्य
प्रकाशित: (2014-01-01)

Role of Notch ligands in tumour angiogenesis
द्वारा: Oon, C
प्रकाशित: (2011)

Genome-wide analysis of the hypoxic breast cancer transcriptome using next generation sequencing
द्वारा: Choudhry, H
प्रकाशित: (2014)

Intestinal epithelial glucocorticoid receptor promotes chronic inflammation–associated colorectal cancer
द्वारा: Shuang Tang, और अन्य
प्रकाशित: (2021-12-01)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
द्वारा: Phipps, L
प्रकाशित: (2011)

The role of homeobox gene NKX3.1 in prostate cancer
द्वारा: Patel, R
प्रकाशित: (2014)

Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress
द्वारा: Samantha N. Devenport, और अन्य
प्रकाशित: (2021-07-01)

LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3
द्वारा: Kensuke Sugiura, और अन्य
प्रकाशित: (2023-07-01)

Selective targeting of homologous recombination deficiency
द्वारा: Zimmer, J
प्रकाशित: (2014)