Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia.
We previously described the first reported isolation of methicillin-resistant Staphylococcus aureus (MRSA) (a case series of pediatric community-associated MRSA infections) in Cambodia. We define the rate of pediatric MRSA carriage in the same population and characterize the associated bacterial gen...
| Главные авторы: | , , , , , , , , , , |
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| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
2011
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| _version_ | 1826288780478251008 |
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| author | Nickerson, E Wuthiekanun, V Kumar, V Amornchai, P Wongdeethai, N Chheng, K Chantratita, N Putchhat, H Thaipadungpanit, J Day, N Peacock, S |
| author_facet | Nickerson, E Wuthiekanun, V Kumar, V Amornchai, P Wongdeethai, N Chheng, K Chantratita, N Putchhat, H Thaipadungpanit, J Day, N Peacock, S |
| author_sort | Nickerson, E |
| collection | OXFORD |
| description | We previously described the first reported isolation of methicillin-resistant Staphylococcus aureus (MRSA) (a case series of pediatric community-associated MRSA infections) in Cambodia. We define the rate of pediatric MRSA carriage in the same population and characterize the associated bacterial genotypes by using pulsed-field gel electrophoresis and multilocus sequence typing. A prospective cohort study of MRSA carriage conducted over one month at the Angkor Hospital for Children, Siem Reap, Cambodia, identified MRSA carriage in 87 (3.5%) of 2,485 children who came to the outpatient department, and 6 (4.1%) of 145 inpatients, including at least two with cases of nosocomial acquisition. Genotyping of all 93 MRSA isolates resolved 5 genotypes. Most (91%) isolates were assigned to sequence type 834. Only 28 (32%) of 87 MRSA carriers identified in the outpatient department had no history of recent healthcare contact. The study findings have important implications for healthcare in a setting where diagnostic microbiology and access to antimicrobial drugs with efficacy against MRSA are limited. |
| first_indexed | 2024-03-07T02:18:52Z |
| format | Journal article |
| id | oxford-uuid:a338e32e-dd6c-4f04-8529-3b56b3d092c8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:18:52Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:a338e32e-dd6c-4f04-8529-3b56b3d092c82022-03-27T02:25:23ZEmergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a338e32e-dd6c-4f04-8529-3b56b3d092c8EnglishSymplectic Elements at Oxford2011Nickerson, EWuthiekanun, VKumar, VAmornchai, PWongdeethai, NChheng, KChantratita, NPutchhat, HThaipadungpanit, JDay, NPeacock, SWe previously described the first reported isolation of methicillin-resistant Staphylococcus aureus (MRSA) (a case series of pediatric community-associated MRSA infections) in Cambodia. We define the rate of pediatric MRSA carriage in the same population and characterize the associated bacterial genotypes by using pulsed-field gel electrophoresis and multilocus sequence typing. A prospective cohort study of MRSA carriage conducted over one month at the Angkor Hospital for Children, Siem Reap, Cambodia, identified MRSA carriage in 87 (3.5%) of 2,485 children who came to the outpatient department, and 6 (4.1%) of 145 inpatients, including at least two with cases of nosocomial acquisition. Genotyping of all 93 MRSA isolates resolved 5 genotypes. Most (91%) isolates were assigned to sequence type 834. Only 28 (32%) of 87 MRSA carriers identified in the outpatient department had no history of recent healthcare contact. The study findings have important implications for healthcare in a setting where diagnostic microbiology and access to antimicrobial drugs with efficacy against MRSA are limited. |
| spellingShingle | Nickerson, E Wuthiekanun, V Kumar, V Amornchai, P Wongdeethai, N Chheng, K Chantratita, N Putchhat, H Thaipadungpanit, J Day, N Peacock, S Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia. |
| title | Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia. |
| title_full | Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia. |
| title_fullStr | Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia. |
| title_full_unstemmed | Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia. |
| title_short | Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia. |
| title_sort | emergence of community associated methicillin resistant staphylococcus aureus carriage in children in cambodia |
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