Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.

Vacuum is not the limit: direct analysis in real time (DART), a new MS ionization method, allows probing of pharmaceuticals under atmospheric pressure, thus bypassing lengthy sample preparation steps and enhancing throughput. DART allows rapid screening of solid drugs at almost constant temperature...

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المؤلفون الرئيسيون: Fernández, F, Cody, R, Green, MD, Hampton, C, Mcgready, R, Sengaloundeth, S, White, N, Newton, P
التنسيق: Journal article
اللغة:English
منشور في: 2006
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author Fernández, F
Cody, R
Green, MD
Hampton, C
Mcgready, R
Sengaloundeth, S
White, N
Newton, P
author_facet Fernández, F
Cody, R
Green, MD
Hampton, C
Mcgready, R
Sengaloundeth, S
White, N
Newton, P
author_sort Fernández, F
collection OXFORD
description Vacuum is not the limit: direct analysis in real time (DART), a new MS ionization method, allows probing of pharmaceuticals under atmospheric pressure, thus bypassing lengthy sample preparation steps and enhancing throughput. DART allows rapid screening of solid drugs at almost constant temperature which decreases errors in mass measurement and improves the identification of potentially harmful unknowns. This is important for identifying counterfeit drugs (fake hologram shown). © 2006 Wiley-VCH Verlag GmbH and Co. KGaA.
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spelling oxford-uuid:a3576fc1-5d86-4ea7-ab6c-d0fc5fe7ea1a2022-03-27T02:26:16ZCharacterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a3576fc1-5d86-4ea7-ab6c-d0fc5fe7ea1aEnglishSymplectic Elements at Oxford2006Fernández, FCody, RGreen, MDHampton, CMcgready, RSengaloundeth, SWhite, NNewton, PVacuum is not the limit: direct analysis in real time (DART), a new MS ionization method, allows probing of pharmaceuticals under atmospheric pressure, thus bypassing lengthy sample preparation steps and enhancing throughput. DART allows rapid screening of solid drugs at almost constant temperature which decreases errors in mass measurement and improves the identification of potentially harmful unknowns. This is important for identifying counterfeit drugs (fake hologram shown). © 2006 Wiley-VCH Verlag GmbH and Co. KGaA.
spellingShingle Fernández, F
Cody, R
Green, MD
Hampton, C
Mcgready, R
Sengaloundeth, S
White, N
Newton, P
Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.
title Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.
title_full Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.
title_fullStr Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.
title_full_unstemmed Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.
title_short Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.
title_sort characterization of solid counterfeit drug samples by desorption electrospray ionization and direct analysis in real time coupled to time of flight mass spectrometry
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