Biochemical and cellular studies of the KDM6 sub-family of JmjC histone lysine demethylases
<p>The JmjC domain containing histone lysine demethylases (JmjC-KDMs) are a family of epigenetic enzymes which regulate gene expression by catalysing demethylation of N-terminal lysines on histone tails. KDM6A and KDM6B catalyse demethylation of histone H3 trimethyllysine (H3K27Me3) on the ta...
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| Formato: | Thesis |
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2018
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