The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa

The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa

Antibiotic resistance carries a fitness cost that must be overcome in order for resistance to persist over the long term. Compensatory mutations that recover the functional defects associated with resistance mutations have been argued to play a key role in overcoming the cost of resistance, but comp...

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Autors principals:	Qi, Q, Toll-Riera, M, Heilbron, K, Preston, G, MacLean, R
Format:	Journal article
Idioma:	English
Publicat:	Royal Society 2016

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