Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation.
Paget's disease is a focal disorder of bone remodelling, in which there is an increase in osteoclast formation. A rare complication of Paget's disease is the development of a sarcoma, most commonly an osteosarcoma. Osteoclast formation occurs in the presence of macrophage-colony stimulatin...
मुख्य लेखकों: | Sun, S, Lau, Y, Itonaga, I, Sabokbar, A, Athanasou, N |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2006
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समान संसाधन
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Osteoclast differentiation in Paget's disease is hypersensitive to RANKL.
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Heterotopic bone formation following hip arthroplasty in Paget's disease.
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RANKL-independent osteoclastogenesis in Paget's disease
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Human osteoclast formation and bone resorption by a mechanism independent of RANK/RANKL: Role of IL-6 and IL-11.
द्वारा: Kudo, O, और अन्य
प्रकाशित: (2001)