Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation.
Paget's disease is a focal disorder of bone remodelling, in which there is an increase in osteoclast formation. A rare complication of Paget's disease is the development of a sarcoma, most commonly an osteosarcoma. Osteoclast formation occurs in the presence of macrophage-colony stimulatin...
| Huvudupphovsmän: | , , , , |
|---|---|
| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
2006
|