Effort but not reward sensitivity is altered by acute sickness induced by experimental endotoxemia in humans

Effort but not reward sensitivity is altered by acute sickness induced by experimental endotoxemia in humans

Sickness behavior in humans is characterized by low mood and fatigue, which have been suggested to reflect changes in motivation involving reorganization of priorities. However, it is unclear which specific processes underlying motivation are altered. We tested whether bacterial endotoxin E. coli li...

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Xehetasun bibliografikoak
Egile Nagusiak:	Draper, A, Koch, R, van der Meer, J, Apps, M, Pickkers, P, Husain, M, van der Schaaf, M
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	Springer Nature 2017

Antzeko izenburuak

The role of cognitive effort in subjective reward devaluation and risky decision-making
nork: Apps, M, et al.
Argitaratua: (2015)

Hypoxia attenuates inflammation-induced hepcidin synthesis during experimental human endotoxemia
nork: Dorien Kiers, et al.
Argitaratua: (2019-06-01)

Transcriptome kinetics of circulating neutrophils during human experimental endotoxemia.
nork: Stan de Kleijn, et al.
Argitaratua: (2012-01-01)

Preferences for seeking effort or reward information bias the willingness to work
nork: Tanja Müller, et al.
Argitaratua: (2022-11-01)

Dissociation of reward and effort sensitivity in methcathinone-induced Parkinsonism
nork: Chong, T, et al.
Argitaratua: (2017)

No Reason to Feel Sick? Nocebo Responses in the Placebo Arms of Experimental Endotoxemia Studies
nork: Sven Benson, et al.
Argitaratua: (2019-07-01)

Atazanavir-induced unconjugated hyperbilirubinemia prevents vascular hyporeactivity during experimental human endotoxemia
nork: Mirrin J. Dorresteijn, et al.
Argitaratua: (2023-05-01)

Characterization of reward and effort mechanisms in apathy.
nork: Bonnelle, V, et al.
Argitaratua: (2015)

Commentary: Noradrenaline and dopamine neurons in the reward/effort trade-off: a direct electrophysiological comparison in behaving monkeys
nork: Ang, Y, et al.
Argitaratua: (2015)

Comparison of different lots of endotoxin and evaluation of potency over time in the experimental human endotoxemia model
nork: Dorien Kiers, et al.
Argitaratua: (2019-01-01)

The effect of iron loading and iron chelation on the innate immune response and subclinical organ injury during human endotoxemia: a randomized trial
nork: Lucas T. van Eijk, et al.
Argitaratua: (2014-03-01)

Histopathological alterations in kidney tissue following experimental endotoxemia in a murine model
nork: Vitaliy Antoniuk, et al.
Argitaratua: (2025-02-01)

Endotoxemia-Induced Release of Pro-inflammatory Mediators Are Associated With Increased Glomerular Filtration Rate in Humans in vivo
nork: Remi Beunders, et al.
Argitaratua: (2020-11-01)

Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection
nork: Natasja de Bont, et al.
Argitaratua: (1999-04-01)

Dopamine enhances willingness to exert effort for reward in Parkinson's disease.
nork: Chong, T, et al.
Argitaratua: (2015)

Reduced pupillary reward sensitivity in Parkinson’s disease
nork: Manohar, S, et al.
Argitaratua: (2015)

Human ventromedial prefrontal lesions alter incentivisation by reward
nork: Manohar, S, et al.
Argitaratua: (2016)

The effects of monetary rewards on volunteers' effort - experimental evidence in Singapore.
nork: Liow, Jia Min., et al.
Argitaratua: (2013)

Leukocytosis and enhanced susceptibility to endotoxemia but not atherosclerosis in adrenalectomized APOE knockout mice.
nork: Menno Hoekstra, et al.
Argitaratua: (2013-01-01)

Covert expectation-of-reward in rat ventral striatum at decision points
nork: Matthijs A A Van Der Meer, et al.
Argitaratua: (2009-02-01)

On effort–reward imbalance and depression
nork: Töres Theorell
Argitaratua: (2017-07-01)

Altered gut microbiota after traumatic splenectomy is associated with endotoxemia
nork: Hua Zhu, et al.
Argitaratua: (2018-11-01)

Neurocomputational mechanisms underlying valuation of effort costs
nork: Chong, T, et al.
Argitaratua: (2017)

Calcium-Sensitive Receptors Alters Intestinal Microbiota Metabolites Especially SCFAs and Ameliorates Intestinal Barrier Damage in Neonatal Rat Endotoxemia
nork: Sun Y, et al.
Argitaratua: (2023-08-01)

Amphetamine sensitization alters reward processing in the human striatum and amygdala.
nork: Owen G O'Daly, et al.
Argitaratua: (2014-01-01)

Impulsivity and rapid decision-making for reward.
nork: Burnett Heyes, S, et al.
Argitaratua: (2012)

Reward pays the cost of noise reduction in motor and cognitive control
nork: Manohar, S, et al.
Argitaratua: (2015)

2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia
nork: Susan F. Fitzpatrick, et al.
Argitaratua: (2020-03-01)

Endotoxemia by Porphyromonas gingivalis Alters Endocrine Functions in Brown Adipose Tissue
nork: Masahiro Hatasa, et al.
Argitaratua: (2021-01-01)

Gamma-Irradiated Bacille Calmette-Guérin Vaccination Does Not Modulate the Innate Immune Response during Experimental Human Endotoxemia in Adult Males
nork: Linda A. C. Hamers, et al.
Argitaratua: (2015-01-01)

The anterior cingulate gyrus signals the net value of others' rewards.
nork: Apps, M, et al.
Argitaratua: (2014)

Altered response to Toll-like receptor 4 activation in fibromyalgia: A low-dose, human experimental endotoxemia pilot study
nork: Chloe Jones, et al.
Argitaratua: (2023-12-01)

Reward sensitivity deficits underlie apathy in Parkinson's disease
nork: Muhammed, K, et al.
Argitaratua: (2015)

Neural and computational mechanisms of momentary fatigue and persistence in effort-based choice
nork: Müller, T, et al.
Argitaratua: (2021)

Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
nork: Maurizio Turzo, et al.
Argitaratua: (2018-02-01)

Effects of subanesthetic doses of ketamine in cats with induced experimental endotoxemia
nork: Felipe Hertzing Farias, et al.
Argitaratua: (2015-12-01)

Correction: Amphetamine Sensitization Alters Reward Processing in the Human Striatum and Amygdala.
nork: Owen G O'Daly, et al.
Argitaratua: (2019-01-01)

Effect of social influence on effort-allocation for monetary rewards.
nork: Jodi M Gilman, et al.
Argitaratua: (2015-01-01)

Prosocial apathy when helping others is too much effort
nork: Lockwood, P, et al.
Argitaratua: (2017)

Reward sensitivity and action in Parkinson’s disease patients with and without apathy
nork: Muhammed, K, et al.
Argitaratua: (2021)