Cyclic changes in the affinity of protein–DNA interactions drive the progression and regulate the outcome of the Tn 10 transposition reaction
The Tn 10 transpososome is a DNA processing machine in which two transposon ends, a transposase dimer and the host protein integration host factor (IHF), are united in an asymmetrical complex. The transitions that occur during one transposition cycle are not limited to chemical cleavage events at th...
Main Authors: | Liu, D, Crellin, P, Chalmers, R |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2005
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