The therapeutic potential of acetyl-lysine and methyl-lysine effector domains

Epigenetic reader domains are protein interaction modules that selectively recognize common post-translational modification on histones and other nuclear proteins such as ε-N-acetylated lysine or methyllysine/arginine residues. Interactions mediated by these effector domains result in the recruitmen...

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Hlavní autoři: Brennan, P, Filippakopoulos, P, Knapp, S
Médium: Journal article
Jazyk:English
Vydáno: 2012