Synthesis of polysubstituted fused pyrroles by gold-catalyzed cycloisomerization/1,2-sulfonyl migration of yndiamides

Synthesis of polysubstituted fused pyrroles by gold-catalyzed cycloisomerization/1,2-sulfonyl migration of yndiamides

Yndiamides (bis-N-substituted alkynes) are valuable precursors to azacycles. Here we report a cycloisomerization/1,2-sulfonyl migration of alkynyl-yndiamides to form tetrahydropyrrolopyrroles, unprecedented heterocyclic scaffolds that are relevant to medicinal chemistry. This functional group tolera...

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Bibliographic Details
Main Authors:	Smith, PJ, Jiang, Y, Tong, Z, Pickford, HD, Christensen, KE, Nugent, J, Anderson, EA
Format:	Journal article
Language:	English
Published:	American Chemical Society 2021

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