Structural and functional studies of Wnt signalling pathway antagonists

Structural and functional studies of Wnt signalling pathway antagonists

<p>Wnt morphogens control embryonic development and adult tissue homeostasis. Deregulation of the Wnt signalling pathway leads to human diseases. This thesis covers work on two antagonists of the Wnt signalling pathway, Wnt inhibitory factor 1 (WIF-1) (Chapters 1 to 5) and secreted Frizzled-re...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Malinauskas, T
अन्य लेखक:	Jones, E
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2011
विषय:	Biology (medical sciences) Biology Molecular biophysics (biochemistry) Biochemistry Oncology

समान संसाधन

Biophysical studies of membrane protein structure and function
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प्रकाशित: (2014)

Structural and functional studies of the hedgehog signalling pathway
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Mutational analysis of isoform selectivity and conformational equilibria in protein kinase inhibition
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प्रकाशित: (2015)

Structure-function studies of the bacterial dsDNA translocase FtsK
द्वारा: Graham, JE
प्रकाशित: (2010)

Single-molecule imaging of electroporated chemotaxis proteins in live bacteria
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प्रकाशित: (2015)

Ion channels: a first view of K⁺ channels in atomic glory
द्वारा: Sansom, M
प्रकाशित: (1998)

Mass Photometry of Membrane Proteins
द्वारा: Olerinyova, A, और अन्य
प्रकाशित: (2020)

Adapting nanobody scaffolds as protein chaperones for effective crystallization and good protein behaviour in cryo-EM
द्वारा: Ye, M
प्रकाशित: (2021)

Physical biology : from atoms to medicine /
द्वारा: Zewail, Ahmed
प्रकाशित: (2008)

Structural studies of a membrane embedded chloride channel from E.Coli, a prokaryotic homologue of ClC channels
द्वारा: Bowler, M, और अन्य
प्रकाशित: (2001)

Structural and functional studies of chromatin modifying enzymes
द्वारा: Walport, L
प्रकाशित: (2013)

Structural studies of Norrin dependent Wnt/beta-catenin signaling
द्वारा: Chang, T
प्रकाशित: (2014)

Biophysical and magnetic resonance studies of membrane proteins
द्वारा: Orwick, M, और अन्य
प्रकाशित: (2011)

Structural studies of malaria proteins
द्वारा: Mayer, C
प्रकाशित: (2012)

Molecular dynamics study of water and Na⁺ ions in models of the pore region of the nicotinic acetylcholine receptor
द्वारा: Smith, G, और अन्य
प्रकाशित: (1997)

Structural, biochemical and computational studies of TRP channel transmembrane domain modularity
द्वारा: Hanson, S
प्रकाशित: (2014)

Structural studies of cell adhesion and division
द्वारा: Yates, LA
प्रकाशित: (2012)

Structural analysis of Wnt signalling pathways
द्वारा: Ruza, RR
प्रकाशित: (2021)

Computational studies of signalling at the cell membrane
द्वारा: Lumb, CN
प्रकाशित: (2012)

Ion channels: structure of a molecular brake
द्वारा: Sansom, M
प्रकाशित: (1999)

Combined effects of double mutations on catalytic activity and structural stability contribute to clinical manifestations of glucose-6-phosphate dehydrogenase deficiency
द्वारा: Pakparnich, P, और अन्य
प्रकाशित: (2021)

The regulation and inhibition of P-TEFb
द्वारा: Hole, A
प्रकाशित: (2011)

Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues
द्वारा: Labro, A, और अन्य
प्रकाशित: (2008)

Interactions of Neisseria meningitidis with the human immune system
द्वारा: Harding, R
प्रकाशित: (2015)

Radiation damage in protein crystals examined under various conditions by different methods
द्वारा: Garman, E, और अन्य
प्रकाशित: (2009)

Determination of X-ray flux using silicon pin diodes
द्वारा: Owen, R, और अन्य
प्रकाशित: (2009)

Structural studies on determinants of receptor/ligand binding in the tumour necrosis factor and T cell receptor protein families
द्वारा: Marles-Wright, J
प्रकाशित: (2005)

Structural studies on determinants of receptor/ligand binding in the tumour necrosis factor and T cell receptor protein families
द्वारा: Marles-Wright, J
प्रकाशित: (2005)

Molecular and structural characterisation of the human Fibrillin-1 N-C terminal interaction
द्वारा: Yadin, D
प्रकाशित: (2013)

Pushing the boundaries: molecular dynamics simulations of complex biological membranes
द्वारा: Parton, D
प्रकाशित: (2011)

Fluorescence studies of influenza RNA and RNA polymerase
द्वारा: Tomescu, A
प्रकाशित: (2014)

Structural characterisation of the interaction between Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) and their human ligands in severe malaria
द्वारा: Ng, HK
प्रकाशित: (2012)

Structural studies of cell surface signalling molecules for neuronal guidance and connectivity
द्वारा: Mitakidis, N
प्रकाशित: (2013)

Mechanisms of transcription regulation by full-length CREB
द्वारा: Jeremie Gaudez
प्रकाशित: (2023)

Electrical interactions in molecular biophysics : an introduction/
द्वारा: 421226 Gabler, Raymond
प्रकाशित: (1978)

Investigating the role of lipids and small-molecule ligands in hedgehog signalling using molecular dynamics simulations
द्वारा: Ansell, T
प्रकाशित: (2022)

A biophysical study of the G protein coupled receptor neurotensin receptor 1
द्वारा: Harding, PJ
प्रकाशित: (2007)

Studying the function and regulation of non-coding transcription in fission yeast by the exosome complex
द्वारा: Shah, S
प्रकाशित: (2014)

The linear ubiquitin assembly complex’s recruitment to signaling complexes: The role of HOIP’s zinc finger domains
द्वारा: Nathanail, E
प्रकाशित: (2021)

Modern experimental biochemistry /
द्वारा: 324400 Boyer, Rodney F.
प्रकाशित: (1993)