Human cleavage factor I (CFIm) and its role in alternative polyadenylation of pre-mRNA

<p>For many human protein-coding genes, alternative cleavage and polyadenylation (APA) of pre-mRNA generates distinct 3' untranslated regions (3'UTRs) with differing regulatory potential. Widespread 3'UTR shortening via APA occurs in proliferative cell states, including cancer,...

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Bibliographic Details
Main Author: Hardy, J
Other Authors: Norbury, C
Format: Thesis
Language:English
Published: 2017
Subjects: