Diverse Fab specific for acetylcholine receptor epitopes from a myasthenia gravis thymus combinatorial library.
The muscle weakness in myasthenia gravis (MG) is caused by heterogeneous high-affinity IgG autoantibodies to the nicotinic acetylcholine receptor (AChR), a complex ion channel glycoprotein. These antibodies are clearly responsible for reducing AChR numbers at the neuromuscular junction in myasthenia...
| Glavni autori: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
1997
|