Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer.

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer.

Major histocompatibility complex (MHC) class I molecules present peptides derived from the endogenous protein pool to cytotoxic T lymphocytes, which can thus recognize intracellular antigen. This pathway may depend on a transporter (PSF1) to mediate entry of the cytosolic peptides into a pre-Golgi c...

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Bibliographic Details
Main Authors:	Spies, T, Cerundolo, V, Colonna, M, Cresswell, P, Townsend, A, DeMars, R
Format:	Journal article
Language:	English
Published:	1992

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