Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia, and it strongly predisposes to esophageal adenocarcinoma (EAC), a tumor with a very poor prognosis. We report the first genome-wide association study on Bar...

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Hlavní autoři:	Su, Z, Gay, L, Strange, A, Palles, C, Band, G, Whiteman, D, Lescai, F, Langford, C, Nanji, M, Edkins, S, van der Winkel, A, Levine, D, Sasieni, P, Bellenguez, C, Howarth, K, Freeman, C, Trudgill, N, Tucker, A, Pirinen, M, Peppelenbosch, M, van der Laan, L, Kuipers, E, Drenth, J, Peters, W, Reynolds, J
Médium:	Journal article
Jazyk:	English
Vydáno:	2012

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

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