Osteopontin is not required for the development of Th1 responses and viral immunity.

Osteopontin is not required for the development of Th1 responses and viral immunity.

Osteopontin (OPN) has been defined as a key cytokine promoting the release of IL-12 and hence inducing the development of protective cell-mediated immunity to viruses and intracellular pathogens. To further characterize the role of OPN in antiviral immunity, OPN-deficient (OPN-/-) mice were analyzed...

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Autors principals:	Abel, B, Freigang, S, Bachmann, M, Boschert, U, Kopf, M
Format:	Journal article
Idioma:	English
Publicat:	2005

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