Serial brain MRI at 3-6 month intervals as a surrogate marker for Alzheimer's disease

A surrogate marker is needed for Alzheimer's disease (AD) both to aid diagnosis and to assess interventions. Despite widespread use, brain imaging markers have largely been confounded by overlap with "normal" ageing. 39 elderly subjects completed up to four serial volumetric brain MRI...

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Main Authors: Bradley, K, Bydder, G, Budge, M, Hajnal, J, White, S, Ripley, B, Smith, A
格式: Journal article
语言:English
出版: British Institute of Radiology 2002