MyD88 adaptor-like D96N is a naturally occurring loss-of-function variant of TIRAP.

MyD88 adaptor-like D96N is a naturally occurring loss-of-function variant of TIRAP.

Signals elicited by TLRs following the detection of microbes are integrated and diversified by a group of four cytoplasmic adaptor molecules featuring an evolutionarily conserved Toll/IL-1R signaling domain. Single nucleotide polymorphisms (SNPs) in TLRs and their adaptor molecules have been shown t...

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Bibliographic Details
Main Authors: George, J, Kubarenko, A, Rautanen, A, Mills, T, Colak, E, Kempf, T, Hill, A, Nieters, A, Weber, A
Format: Journal article
Language:English
Published: 2010

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