Characterising immune responses to viral vectored vaccines against influenza and hepatitis C

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C

<p>For both influenza viruses and hepatitis C viruses, T cell responses to conserved antigens are one strategy for the human host to control the spread of infection. Such T cell responses can be generated with the use of viral vectored vaccines.</p> <p>Initially I show that the vir...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Antrobus, R
Awduron Eraill:	Gilbert, S
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2014
Pynciau:	Medical Sciences Infectious diseases Vaccinology Immunology

Eitemau Tebyg

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Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
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Innate immune responses to tuberculosis vaccines
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Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination
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Biodegradable pulsatile release technologies for viral vector based vaccinations
gan: Krastev, C
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New approaches for improving the immunogenicity of modified vaccinia virus Ankara as a recombinant vaccine vector
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Analysis of b cell responses to blood-stage malaria antigens in humans following immunization with candidate vaccines and controlled human malaria infection
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Characterisation of T cells induced by candidate conserved region HIV-1 vaccines in healthy HIV-1/2 negative volunteers
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Enhancing the efficacy of viral vector blood-stage malaria vaccines
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Development of antimalarial human monoclonal antibodies against Plasmodium falciparum
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Evaluation of immune correlates to TB vaccines
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B cell responses to conjugate and polysaccharide meningococcal vaccines
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Understanding the link between interleukin 17 and vaccine-induced protection in tuberculosis
gan: Griffiths, K
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Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
gan: Matsumiya, M, et al.
Cyhoeddwyd: (2014)

Evaluation of a potential vaccine against hyperinvasive serogroup B Neisseria meningitidis by assessment of the effects of surface-expressed Opacity-associated proteins on the immune system
gan: Sadarangani, M
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Malaria pre-erythrocytic stage vaccines: targeting antigen combinations
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Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens
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HIV-specific interleukin-10 responses and immune modulation
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Evaluation of the immunogenicity of a promising vaccine regimen to identify immune correlates of protection
gan: Pinpathomrat, N
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B cell response to pneumococcal vaccines
gan: Trück, J
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Long term efficacy of a pre-erythrocytic malaria vaccine and correlates of protection in children residing in a malaria endemic country
gan: Olotu, A
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Apoptosis and other immune biomarkers predict influenza vaccine responsiveness
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Cyhoeddwyd: (2013-04-01)

The design and development of an HIV-1 vaccine to elicit a broadly neutralising antibody response
gan: Wan, L, et al.
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Genetics determinants of vaccine responses
gan: O'Connor, D
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Innate immune pathways controlling IL-1beta production and adjuvant-induced T helper 17 cell differentiation
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Cyhoeddwyd: (2011)

The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM197 conjugate vaccine
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Cyhoeddwyd: (2006)

Evaluation of the immunological mechanisms induced by mycobacteria and the potential effect this may have on immunity induced by tuberculosis vaccines
gan: Poyntz, HC
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Developing novel blood-stage malaria vaccines
gan: Douglas, AD
Cyhoeddwyd: (2015)

Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches
gan: Pearson, FE
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Investigating novel mechanisms of immunity against enteric fever
gan: Johnson, M
Cyhoeddwyd: (2022)

Control of typhoid fever: evaluating herd protection through public health use of typhoid VI polysaccharide vaccine
gan: Ochiai, R
Cyhoeddwyd: (2011)

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations
gan: Hanekom, W, et al.
Cyhoeddwyd: (2008)

Towards the development of multi-disease vaccines against arthropod-borne viruses
gan: Montalvo Zurbía Flores, G
Cyhoeddwyd: (2022)

Effect of needle size on immunogenicity and reactogenicity of vaccines in infants: randomised controlled trial
gan: Diggle, L, et al.
Cyhoeddwyd: (2006)

Influence of genetic and environmental factors on the immunogenicity of Hib vaccine in Gambian twins
gan: Lee, Y, et al.
Cyhoeddwyd: (2006)

T-cell receptor (TCR) usage in HIV-2 infection
gan: Moysi, E
Cyhoeddwyd: (2012)