Regulation of the angiopoietin-Tie ligand-receptor system with a novel splice variant of Tie1 reduces the severity of murine arthritis.

Regulation of the angiopoietin-Tie ligand-receptor system with a novel splice variant of Tie1 reduces the severity of murine arthritis.

OBJECTIVES: To determine the function of the angiopoietin (Ang)-Tie ligand-receptor system, and to assess the effect of Tie1-751, a naturally occurring extracellular domain of the Tie1 receptor derived by alternative splicing, in an in vivo model of RA. METHODS: In the murine CIA model, expression...

书目详细资料
Main Authors:	Malik, N, Jin, P, Raatz, Y, Sumariwalla, P, Kiriakidis, S, Shepard, M, Feldmann, M, Paleolog, E
格式:	Journal article
语言:	English
出版:	2010

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