Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients

We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate gene CCND1 have on the development of multiple intestinal adenomas and the early onset of colorectal cancer. Individuals with <100 multiple polyps and patients with colorectal cancer diagnosed...

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Main Authors: Bonilla, C, Lefèvre, J, Winney, B, Johnstone, E, Tonks, S, Colas, C, Day, T, Hutnik, K, Boumertit, A, Midgley, R, Kerr, D, Parc, Y, Bodmer, W
格式: Journal article
语言:English
出版: Nature Publishing Group 2015