Comparison of mortality prediction models after open abdominal aortic aneurysm repair.
OBJECTIVES: Comparison of the accuracy of prediction of contemporary mortality prediction models after open Abdominal Aortic Aneurysm (AAA) surgery. METHODS: Post-operative data were collected from AAA patients from 2 UK Intensive Care Units (ICU). POSSUM and VBHOM based models were compared to the...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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| _version_ | 1797086406156222464 |
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| author | Hadjianastassiou, V Tekkis, P Athanasiou, T Muktadir, A Young, J Hands, L |
| author_facet | Hadjianastassiou, V Tekkis, P Athanasiou, T Muktadir, A Young, J Hands, L |
| author_sort | Hadjianastassiou, V |
| collection | OXFORD |
| description | OBJECTIVES: Comparison of the accuracy of prediction of contemporary mortality prediction models after open Abdominal Aortic Aneurysm (AAA) surgery. METHODS: Post-operative data were collected from AAA patients from 2 UK Intensive Care Units (ICU). POSSUM and VBHOM based models were compared to the APACHE-AAA model which was able to adjust for the hospital-related effect on outcome. Model performance was assessed using measures of calibration, discrimination and subgroup analysis. RESULTS: 541 patients were studied. The in-hospital mortality rate for elective AAA repair (325 patients) was: 6.2% (95% confidence interval (c.i.) 3.5 to 8.8) and for emergency repair (216 patients) was: 28.7% (95% c.i. 22.5-34.9). The APACHE-based model had the best overall fit to the whole population of AAA patients, and also separately in elective and emergency patients. The V-POSSUM physiology-only (p<0.001) and VBHOM (p=0.011) models had a poor fit in elective patients. The RAAA-POSSUM physiology-only (p<0.001) and VBHOM models (p=0.010) had a poor fit in emergency patients. CONCLUSIONS: The APACHE-AAA model with its ability to adjust for both the hospital-related "effect" as well as the patient case-mix, was a more accurate risk stratification model than other contemporary models, in the post-operative AAA patient managed in ICU. |
| first_indexed | 2024-03-07T02:21:35Z |
| format | Journal article |
| id | oxford-uuid:a41af92c-eab5-44e2-a45f-bcc7d6cefd0c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:21:35Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:a41af92c-eab5-44e2-a45f-bcc7d6cefd0c2022-03-27T02:32:08ZComparison of mortality prediction models after open abdominal aortic aneurysm repair.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a41af92c-eab5-44e2-a45f-bcc7d6cefd0cEnglishSymplectic Elements at Oxford2007Hadjianastassiou, VTekkis, PAthanasiou, TMuktadir, AYoung, JHands, LOBJECTIVES: Comparison of the accuracy of prediction of contemporary mortality prediction models after open Abdominal Aortic Aneurysm (AAA) surgery. METHODS: Post-operative data were collected from AAA patients from 2 UK Intensive Care Units (ICU). POSSUM and VBHOM based models were compared to the APACHE-AAA model which was able to adjust for the hospital-related effect on outcome. Model performance was assessed using measures of calibration, discrimination and subgroup analysis. RESULTS: 541 patients were studied. The in-hospital mortality rate for elective AAA repair (325 patients) was: 6.2% (95% confidence interval (c.i.) 3.5 to 8.8) and for emergency repair (216 patients) was: 28.7% (95% c.i. 22.5-34.9). The APACHE-based model had the best overall fit to the whole population of AAA patients, and also separately in elective and emergency patients. The V-POSSUM physiology-only (p<0.001) and VBHOM (p=0.011) models had a poor fit in elective patients. The RAAA-POSSUM physiology-only (p<0.001) and VBHOM models (p=0.010) had a poor fit in emergency patients. CONCLUSIONS: The APACHE-AAA model with its ability to adjust for both the hospital-related "effect" as well as the patient case-mix, was a more accurate risk stratification model than other contemporary models, in the post-operative AAA patient managed in ICU. |
| spellingShingle | Hadjianastassiou, V Tekkis, P Athanasiou, T Muktadir, A Young, J Hands, L Comparison of mortality prediction models after open abdominal aortic aneurysm repair. |
| title | Comparison of mortality prediction models after open abdominal aortic aneurysm repair. |
| title_full | Comparison of mortality prediction models after open abdominal aortic aneurysm repair. |
| title_fullStr | Comparison of mortality prediction models after open abdominal aortic aneurysm repair. |
| title_full_unstemmed | Comparison of mortality prediction models after open abdominal aortic aneurysm repair. |
| title_short | Comparison of mortality prediction models after open abdominal aortic aneurysm repair. |
| title_sort | comparison of mortality prediction models after open abdominal aortic aneurysm repair |
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