ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID

The isolation from Alexa leiopetala and identification by X-ray crystal structure analysis of (1R,2R,3R,7S,8S)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine [(2R,3R,4R,5S,6S)-2-hydroxymethyl-1-azabicyclo[3.3.0]octan-3,4,6-triol], a unique pyrrolizidine alkaloid, is described. A preliminary study of...

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Main Authors: Nash, R, Fellows, L, Dring, J, Fleet, G, Derome, A, Hamor, T, Scofield, A, Watkin, D
Format: Journal article
Language:English
Published: 1988
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author Nash, R
Fellows, L
Dring, J
Fleet, G
Derome, A
Hamor, T
Scofield, A
Watkin, D
author_facet Nash, R
Fellows, L
Dring, J
Fleet, G
Derome, A
Hamor, T
Scofield, A
Watkin, D
author_sort Nash, R
collection OXFORD
description The isolation from Alexa leiopetala and identification by X-ray crystal structure analysis of (1R,2R,3R,7S,8S)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine [(2R,3R,4R,5S,6S)-2-hydroxymethyl-1-azabicyclo[3.3.0]octan-3,4,6-triol], a unique pyrrolizidine alkaloid, is described. A preliminary study of the inhibition of glycosidases by alexine is reported. © 1988.
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spelling oxford-uuid:a4336dc0-ee78-4c2a-96b8-afd7e5b6d40b2022-03-27T02:32:14ZISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOIDJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a4336dc0-ee78-4c2a-96b8-afd7e5b6d40bEnglishSymplectic Elements at Oxford1988Nash, RFellows, LDring, JFleet, GDerome, AHamor, TScofield, AWatkin, DThe isolation from Alexa leiopetala and identification by X-ray crystal structure analysis of (1R,2R,3R,7S,8S)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine [(2R,3R,4R,5S,6S)-2-hydroxymethyl-1-azabicyclo[3.3.0]octan-3,4,6-triol], a unique pyrrolizidine alkaloid, is described. A preliminary study of the inhibition of glycosidases by alexine is reported. © 1988.
spellingShingle Nash, R
Fellows, L
Dring, J
Fleet, G
Derome, A
Hamor, T
Scofield, A
Watkin, D
ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID
title ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID
title_full ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID
title_fullStr ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID
title_full_unstemmed ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID
title_short ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID
title_sort isolation from alexa leiopetala and x ray crystal structure of alexine 1r 2r 3r 7s 8s 3 hydroxymethyl 1 2 7 trihydroxypyrrolizidine 2r 3r 4r 5s 6s 2 hydroxymethyl 1 azabicyclo 3 3 0 octan 3 4 6 triol a unique pyrrolizidine alkaloid
work_keys_str_mv AT nashr isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT fellowsl isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT dringj isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT fleetg isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT deromea isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT hamort isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT scofielda isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid
AT watkind isolationfromalexaleiopetalaandxraycrystalstructureofalexine1r2r3r7s8s3hydroxymethyl127trihydroxypyrrolizidine2r3r4r5s6s2hydroxymethyl1azabicyclo330octan346triolauniquepyrrolizidinealkaloid