Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.

Hepcidin is a liver-derived hormone with a key role in iron homeostasis. In addition to iron, it is regulated by inflammation and hypoxia, although mechanisms of hypoxic regulation remain unclear. In hepatocytes, hepcidin is induced by bone morphogenetic proteins (BMPs) through a receptor complex re...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Lakhal, S, Schödel, J, Townsend, A, Pugh, C, Ratcliffe, P, Mole, D
التنسيق:	Journal article
اللغة:	English
منشور في:	2011

مواد مشابهة

Pan-genomic binding of hypoxia-inducible transcription factors.
حسب: Schödel, J, وآخرون
منشور في: (2013)

Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19
حسب: Rosalinda Posadas-Sánchez, وآخرون
منشور في: (2022-09-01)

TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer
حسب: Semi Kim
منشور في: (2023-04-01)

Mechanisms of hypoxia signalling: new implications for nephrology
حسب: Schödel, J, وآخرون
منشور في: (2019)

COVID-19 pandemic; transmembrane protease serine 2 (TMPRSS2) inhibitors as potential drugs.
حسب: Jerzy Jankun
منشور في: (2020-04-01)

Differentiation modulates the hypoxia-inducible gene program in macrophages: Effects of alterations in iron homeostasis
حسب: Knowles, H, وآخرون
منشور في: (2004)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
حسب: Chan, M, وآخرون
منشور في: (2016)

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron
حسب: Maria Antonietta Melis, وآخرون
منشور في: (2008-10-01)

New horizons in hypoxia signaling pathways
حسب: Pugh, C, وآخرون
منشور في: (2017)

Hypoxia-inducible factors: where, when and why?
حسب: Gleadle, J, وآخرون
منشور في: (2006)

Regulation of angiogenesis by hypoxia: role of the HIF system.
حسب: Pugh, C, وآخرون
منشور في: (2003)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
حسب: Choudhry, H, وآخرون
منشور في: (2014)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
حسب: Choudhry, H, وآخرون
منشور في: (2013)

Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury.
حسب: Ana Valero-Jiménez, وآخرون
منشور في: (2018-01-01)

Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)
حسب: Noor Rahman, وآخرون
منشور في: (2020-05-01)

Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis
حسب: Andrew J. Ramsay, وآخرون
منشور في: (2009-06-01)

PAN-GENOMIC BINDING OF HYPOXIA-INDUCIBLE TRANSCRIPTION FACTORS IN RENAL CANCER CELLS
حسب: Schoedel, J, وآخرون
منشور في: (2013)

Hypoxia response elements.
حسب: O'Rourke, J, وآخرون
منشور في: (1997)

Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex.
حسب: Mole, D, وآخرون
منشور في: (2002)

Regulation of growth differentiation factor 15 expression by intracellular iron.
حسب: Lakhal, S, وآخرون
منشور في: (2009)

Hypoxia Signalling and Disease
حسب: Ratcliffe, P
منشور في: (2010)

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
حسب: Ratcliffe, P
منشور في: (2002)

The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies
حسب: Siming Gao, وآخرون
منشور في: (2018-07-01)

Molecular characterization of a Trichinella spiralis serine proteinase
حسب: Xin Yue, وآخرون
منشور في: (2020-09-01)

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
حسب: Tian, Y, وآخرون
منشور في: (2011)

Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways.
حسب: Pugh, C, وآخرون
منشور في: (2001)

Suppression of plasma hepcidin by venesection during steady-state hypoxia
حسب: Talbot, N, وآخرون
منشور في: (2016)

Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1.
حسب: Knowles, H, وآخرون
منشور في: (2006)

Normoxic stabilization of hypoxia-inducible factor-1α by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1
حسب: Knowles, H, وآخرون
منشور في: (2006)

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
حسب: Webb, J, وآخرون
منشور في: (2009)

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
حسب: Mole, D, وآخرون
منشور في: (2009)

Maintenance of redox homeostasis by hypoxia-inducible factors
حسب: Debangshu Samanta, وآخرون
منشور في: (2017-10-01)

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
حسب: Cockman, M, وآخرون
منشور في: (2000)

Iron, hypoxia and chronic disease
حسب: Santer, P
منشور في: (2018)

The under‐appreciated world of the serpin family of serine proteinase inhibitors
حسب: Marie‐Christine Bouton, وآخرون
منشور في: (2023-05-01)

Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi
حسب: Leah Theresa Sigle, وآخرون
منشور في: (2013-09-01)

Study on Serine Proteinase in the Muscle of Yesso Scallops (Mizuhopecten yessoensis）
حسب: Qiuying REN, وآخرون
منشور في: (2022-08-01)

Hypoxia, hypoxia-inducible factor (HIF) and bone homeostasis: focus on osteoclast-mediated bone resorption
حسب: Knowles, H
منشور في: (2015)

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.
حسب: Navneet Sharma, وآخرون
منشور في: (2011-01-01)

The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.
حسب: Pugh, C, وآخرون
منشور في: (2003)