Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.

Hepcidin is a liver-derived hormone with a key role in iron homeostasis. In addition to iron, it is regulated by inflammation and hypoxia, although mechanisms of hypoxic regulation remain unclear. In hepatocytes, hepcidin is induced by bone morphogenetic proteins (BMPs) through a receptor complex re...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Lakhal, S, Schödel, J, Townsend, A, Pugh, C, Ratcliffe, P, Mole, D
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2011

Ижил төстэй зүйлс

Pan-genomic binding of hypoxia-inducible transcription factors.
-н: Schödel, J, зэрэг
Хэвлэсэн: (2013)

Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19
-н: Rosalinda Posadas-Sánchez, зэрэг
Хэвлэсэн: (2022-09-01)

TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer
-н: Semi Kim
Хэвлэсэн: (2023-04-01)

Mechanisms of hypoxia signalling: new implications for nephrology
-н: Schödel, J, зэрэг
Хэвлэсэн: (2019)

COVID-19 pandemic; transmembrane protease serine 2 (TMPRSS2) inhibitors as potential drugs.
-н: Jerzy Jankun
Хэвлэсэн: (2020-04-01)

Differentiation modulates the hypoxia-inducible gene program in macrophages: Effects of alterations in iron homeostasis
-н: Knowles, H, зэрэг
Хэвлэсэн: (2004)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
-н: Chan, M, зэрэг
Хэвлэсэн: (2016)

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron
-н: Maria Antonietta Melis, зэрэг
Хэвлэсэн: (2008-10-01)

New horizons in hypoxia signaling pathways
-н: Pugh, C, зэрэг
Хэвлэсэн: (2017)

Hypoxia-inducible factors: where, when and why?
-н: Gleadle, J, зэрэг
Хэвлэсэн: (2006)

Regulation of angiogenesis by hypoxia: role of the HIF system.
-н: Pugh, C, зэрэг
Хэвлэсэн: (2003)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
-н: Choudhry, H, зэрэг
Хэвлэсэн: (2014)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
-н: Choudhry, H, зэрэг
Хэвлэсэн: (2013)

Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury.
-н: Ana Valero-Jiménez, зэрэг
Хэвлэсэн: (2018-01-01)

Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)
-н: Noor Rahman, зэрэг
Хэвлэсэн: (2020-05-01)

Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis
-н: Andrew J. Ramsay, зэрэг
Хэвлэсэн: (2009-06-01)

PAN-GENOMIC BINDING OF HYPOXIA-INDUCIBLE TRANSCRIPTION FACTORS IN RENAL CANCER CELLS
-н: Schoedel, J, зэрэг
Хэвлэсэн: (2013)

Hypoxia response elements.
-н: O'Rourke, J, зэрэг
Хэвлэсэн: (1997)

Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex.
-н: Mole, D, зэрэг
Хэвлэсэн: (2002)

Regulation of growth differentiation factor 15 expression by intracellular iron.
-н: Lakhal, S, зэрэг
Хэвлэсэн: (2009)

Hypoxia Signalling and Disease
-н: Ratcliffe, P
Хэвлэсэн: (2010)

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
-н: Ratcliffe, P
Хэвлэсэн: (2002)

The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies
-н: Siming Gao, зэрэг
Хэвлэсэн: (2018-07-01)

Molecular characterization of a Trichinella spiralis serine proteinase
-н: Xin Yue, зэрэг
Хэвлэсэн: (2020-09-01)

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
-н: Tian, Y, зэрэг
Хэвлэсэн: (2011)

Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways.
-н: Pugh, C, зэрэг
Хэвлэсэн: (2001)

Suppression of plasma hepcidin by venesection during steady-state hypoxia
-н: Talbot, N, зэрэг
Хэвлэсэн: (2016)

Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1.
-н: Knowles, H, зэрэг
Хэвлэсэн: (2006)

Normoxic stabilization of hypoxia-inducible factor-1α by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1
-н: Knowles, H, зэрэг
Хэвлэсэн: (2006)

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
-н: Webb, J, зэрэг
Хэвлэсэн: (2009)

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
-н: Mole, D, зэрэг
Хэвлэсэн: (2009)

Maintenance of redox homeostasis by hypoxia-inducible factors
-н: Debangshu Samanta, зэрэг
Хэвлэсэн: (2017-10-01)

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
-н: Cockman, M, зэрэг
Хэвлэсэн: (2000)

Iron, hypoxia and chronic disease
-н: Santer, P
Хэвлэсэн: (2018)

The under‐appreciated world of the serpin family of serine proteinase inhibitors
-н: Marie‐Christine Bouton, зэрэг
Хэвлэсэн: (2023-05-01)

Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi
-н: Leah Theresa Sigle, зэрэг
Хэвлэсэн: (2013-09-01)

Study on Serine Proteinase in the Muscle of Yesso Scallops (Mizuhopecten yessoensis）
-н: Qiuying REN, зэрэг
Хэвлэсэн: (2022-08-01)

Hypoxia, hypoxia-inducible factor (HIF) and bone homeostasis: focus on osteoclast-mediated bone resorption
-н: Knowles, H
Хэвлэсэн: (2015)

Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.
-н: Navneet Sharma, зэрэг
Хэвлэсэн: (2011-01-01)

The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.
-н: Pugh, C, зэрэг
Хэвлэсэн: (2003)