Predicting pharmacological potencies of nitrogen-containing bisphosphonates; novel methods dissociate enzyme- and hydroxyapatite-binding affinities

Míreanna comhchosúla

• Nitrogen-containing bisphosphonates and prediction of their clinical potencies: Dissociation of target enzyme- and hydroxyapatite-binding affinities
  de réir: Xia, Z, et al.
  Foilsithe / Cruthaithe: (2007)
• Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
  de réir: Xia, Z, et al.
  Foilsithe / Cruthaithe: (2006)
• Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
  de réir: Xia, Z, et al.
  Foilsithe / Cruthaithe: (2007)
• A novel method to characterize relative mineral binding affinities of bisphosphonates and the structural requirements for binding by using ceramic hydroxyapatite column chromatography.
  de réir: Xia, Z, et al.
  Foilsithe / Cruthaithe: (2006)
• Differences between bisphosphonates in binding affinities for hydroxyapatite.
  de réir: Lawson, M, et al.
  Foilsithe / Cruthaithe: (2010)