Hemolytic potential of tafenoquine in female volunteers heterozygous for glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PD Mahidol variant) versus G6PD-normal volunteers

Hemolytic potential of tafenoquine in female volunteers heterozygous for glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PD Mahidol variant) versus G6PD-normal volunteers

Tafenoquine is an 8-aminoquinoline under investigation for the prevention of relapse in Plasmodium vivax malaria. This open-label, dose-escalation study assessed quantitatively the hemolytic risk with tafenoquine in female healthy volunteers heterozygous for the Mahidol(487A) glucose-6-phosphate deh...

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Bibliographic Details
Main Authors: Rueangweerayut, R, Bancone, G, Harrell, E, Beelen, A, Kongpatanakul, S, Möhrle, J, Rousell, V, Mohamed, K, Qureshi, A, Narayan, S, Yubon, N, Miller, A, Nosten, F, Luzzatto, L, Duparc, S, Kleim, J, Green, J
Format: Journal article
Language:English
Published: American Society of Tropical Medicine and Hygiene 2017

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