Structural basis for substrate specificity in human monomeric carbonyl reductases.
UNLABELLED: Carbonyl reduction constitutes a phase I reaction for many xenobiotics and is carried out in mammals mainly by members of two protein families, namely aldo-keto reductases and short-chain dehydrogenases/reductases. In addition to their capacity to reduce xenobiotics, several of the enzym...
Hlavní autoři: | , , , , , , , , , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Public Library of Science
2009
|