Ribozymes as therapeutic tools for genetic disease.

Ribozymes as therapeutic tools for genetic disease.

The discovery that RNA can act as a biological catalyst, as well as a genetic molecule, indicated that there was a time when biological reactions were catalysed in the absence of protein-based enzymes. It also provided the platform to develop those catalytic RNA molecules, called ribozymes, as trans...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Phylactou, L, Kilpatrick, M, Wood, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	1998

समान संसाधन

Ribozyme-mediated trans-splicing of a trinucleotide repeat.
द्वारा: Phylactou, L, और अन्य
प्रकाशित: (1998)

The Application of Ribozymes and DNAzymes in Muscle and Brain
द्वारा: Leonidas A. Phylactou, और अन्य
प्रकाशित: (2010-08-01)

Hammerhead ribozymes reduce central nervous system (CNS)-derived neuronal nitric oxide synthase messenger RNA in a human cell line.
द्वारा: Maniotis, D, और अन्य
प्रकाशित: (2002)

Ribozymes and siRNA for the treatment of diseases of the nervous system.
द्वारा: Wood, M, और अन्य
प्रकाशित: (2003)

Expanding the limits of the second genetic code with ribozymes
द्वारा: Joongoo Lee, और अन्य
प्रकाशित: (2019-11-01)

Ribozymes and RNA catalysis /
द्वारा: Lilley, David M. J. David Malcolm James, 1948-, और अन्य
प्रकाशित: (2008)

[RNA polymerase ribozymes]
द्वारा: Lawrence, Michael S. (Michael Scott), 1975-
प्रकाशित: (2008)

Ribozymes : methods and protocols /
द्वारा: Hartig, Jr̲g S.
प्रकाशित: (2012)

Arginine cofactors on the polymerase ribozyme.
द्वारा: Chengguo Yao, और अन्य
प्रकाशित: (2011-01-01)

A reverse transcriptase ribozyme
द्वारा: Biswajit Samanta, और अन्य
प्रकाशित: (2017-09-01)

A Faster Triphosphorylation Ribozyme.
द्वारा: Gregory F Dolan, और अन्य
प्रकाशित: (2015-01-01)

Special Issue: Ribozymes and RNA Catalysis
द्वारा: Sabine Müller
प्रकाशित: (2017-05-01)

Man versus machine versus ribozyme.
द्वारा: Andrew D Ellington
प्रकाशित: (2008-05-01)

Searching for ribozymes with new and improved properties
द्वारा: Curtis, Edward A. (Edward Arthur)
प्रकाशित: (2007)

Ribozyme-based insulator parts buffer synthetic circuits from genetic context
द्वारा: Lou, Chunbo, और अन्य
प्रकाशित: (2014)

A Singular and Widespread Group of Mobile Genetic Elements: RNA Circles with Autocatalytic Ribozymes
द्वारा: Marcos de la Peña, और अन्य
प्रकाशित: (2020-11-01)

The use of ribozymes in gene therapy approaches to AIDS.
द्वारा: James, W
प्रकाशित: (1998)

Computational approaches to the identification of ribozyme target sites.
द्वारा: James, W, और अन्य
प्रकाशित: (1997)

Inhibition of telomerase activity by HDV ribozyme in cancers
द्वारा: Gao Yanjing, और अन्य
प्रकाशित: (2011-01-01)

Structure, dynamics, and mechanism of the lead-dependent ribozyme
द्वारा: Qi Xin, और अन्य
प्रकाशित: (2011-08-01)

Viroid Replication: Rolling-Circles, Enzymes and Ribozymes
द्वारा: Marcos De la Peña, और अन्य
प्रकाशित: (2009-09-01)

Engineering RNA logic with synthetic splicing ribozymes
द्वारा: Che, Austin, 1979-
प्रकाशित: (2009)

Use of 33P for Ribozyme Assays: The Safe Way
द्वारा: Patrice R.A. Wolff, और अन्य
प्रकाशित: (1996-09-01)

Fluorescence Polarization for Monitoring Ribozyme Reactions in Real Time
द्वारा: K.K. Singh, और अन्य
प्रकाशित: (2000-08-01)

RNA ligase ribozymes with a small catalytic core
द्वारा: Yoko Nomura, और अन्य
प्रकाशित: (2023-05-01)

Modulation of Group I Ribozyme Activity by Cationic Porphyrins
द्वारा: Shigeyoshi Matsumura, और अन्य
प्रकाशित: (2015-03-01)

Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly
द्वारा: Saurja DasGupta, और अन्य
प्रकाशित: (2023-08-01)

RiboaptDB: A Comprehensive Database of Ribozymes and Aptamers
द्वारा: Thodima Venkata, और अन्य
प्रकाशित: (2006-09-01)

Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes
द्वारा: Evan Janzen, और अन्य
प्रकाशित: (2022-06-01)

Design principles for ligand-sensing, conformation-switching ribozymes.
द्वारा: Xi Chen, और अन्य
प्रकाशित: (2009-12-01)

Prebiotic Factors Influencing the Activity of a Ligase Ribozyme
द्वारा: Fabrizio Anella, और अन्य
प्रकाशित: (2017-04-01)

Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes
द्वारा: Ki-Young Lee, और अन्य
प्रकाशित: (2017-04-01)

Pressure modulates the self-cleavage step of the hairpin ribozyme
द्वारा: Caroline Schuabb, और अन्य
प्रकाशित: (2017-03-01)

Kinetic barriers to folding in the Tetrahymena group I ribozyme
द्वारा: Rook, Martha S. (Martha Sanderson), 1970-
प्रकाशित: (2009)

OPTIMIZING HAMMERHEAD RIBOZYMES FOR USE AGAINST HIV IN-VIVO
द्वारा: Thompson, S, और अन्य
प्रकाशित: (1995)

RNA Synthesis by in Vitro Selected Ribozymes for Recreating an RNA World
द्वारा: Lyssa L. Martin, और अन्य
प्रकाशित: (2015-01-01)

Many Activities, One Structure: Functional Plasticity of Ribozyme Folds
द्वारा: Matthew W.L. Lau, और अन्य
प्रकाशित: (2016-11-01)

An RNA Triangle with Six Ribozyme Units Can Promote a <i>Trans</i>-Splicing Reaction through Trimerization of Unit Ribozyme Dimers
द्वारा: Junya Akagi, और अन्य
प्रकाशित: (2021-03-01)

The structure and catalytic mechanism of a pseudoknot-containing hammerhead ribozyme
द्वारा: Xuelin Zhan, और अन्य
प्रकाशित: (2024-08-01)

Quantitation of In Vitro Activity of Synthetic Trans-Acting Ribozymes Using HPLC
द्वारा: L. Citti, और अन्य
प्रकाशित: (1997-11-01)