SAMHD1-dependent retroviral control and escape in mice
SAMHD1 is a host restriction factor for human immunodeficiency virus 1 (HIV-1) in cultured human cells. SAMHD1 mutations cause autoimmune Aicardi-Goutières syndrome and are found in cancers including chronic lymphocytic leukaemia. SAMHD1 is a triphosphohydrolase that depletes the cellular pool of de...
Үндсэн зохиолчид: | Rehwinkel, J, Maelfait, J, Bridgeman, A, Rigby, R, Hayward, B, Liberatore, R, Bieniasz, P, Towers, G, Moita, L, Crow, Y, Bonthron, D, Reis E Sousa, C |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2013
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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PNP inhibitors selectively kill cancer cells lacking SAMHD1
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Хэвлэсэн: (2020-11-01)