LLT1 and CD161 expression in human germinal centers promotes B cell activation and CXCR4 downregulation

LLT1 and CD161 expression in human germinal centers promotes B cell activation and CXCR4 downregulation

Germinal centers (GC) are microanatomical structures critical for the development of high-affinity antibodies and B-cell memory. They are organised into two zones, light and dark, with coordinated roles, controlled by local signalling. The innate Lectin-like transcript 1 (LLT1) is known to be expres...

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Hlavní autoři: Llibre, A, López-Macías, C, Marafioti, T, Mehta, H, Partridge, A, Kanzig, C, Rivellese, F, Galson, J, Walker, L, Milne, P, Phillips, R, Kelly, D, Freeman, G, El Shikh, M, Klenerman, P, Willberg, C
Médium: Journal article
Vydáno: American Association of Immunologists 2016

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