Combined deficiencies of endosomal ganglioside neuraminidases 3 and 4 in mice cause lysosomal GM3 gangliosidosis

Combined deficiencies of endosomal ganglioside neuraminidases 3 and 4 in mice cause lysosomal GM3 gangliosidosis

अन्य संस्करण दिखाएं (1)

The sialylated glycosphingolipids gangliosides are essential to myelination, axon integrity, transmission of nervous impulses and memory consolidation. Ganglioside expression patterns in the brain are cell-specific, dynamic and maintained by highly coordinated processes of biosynthesis, trafficking,...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Pshezhetsky, A, Pan, X, De Britto Pará De Aragão, C, Velasco-Martin, J, Priestman, D, Platt, F, Lamarche-Vaned, N, Morales, C, Miyagi, T
स्वरूप:	Conference item
प्रकाशित:	Elsevier 2017

समान संसाधन

Combined deficiencies of endosomal ganglioside neuraminidases 3 and 4 in mice cause lysosomal GM3 gangliosidosis
द्वारा: Pshezhetsky, A, और अन्य
प्रकाशित: (2017)

Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides
द्वारा: Pan, X, और अन्य
प्रकाशित: (2017)

N-butyldeoxygalactonojirimycin reduces postnatal cerebellar ganglioside content in a mouse model of GM1 gangliosidosis
द्वारा: Kasperzyk, J, और अन्य
प्रकाशित: (2004)

N-butyldeoxygalactonojirimycin reduces neonatal brain ganglioside content in a mouse model of GM1 gangliosidosis.
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"Substrate reduction reduces gangliosides in postnatal cerebrum-brainstem and cerebellum in GM1 gangliosidosis mice" (vol 46, pg 744, 2004)
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Altered expression of ganglioside metabolizing enzymes results in GM3 ganglioside accumulation in cerebellar cells of a mouse model of juvenile neuronal ceroid lipofuscinosis
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Erratum: Substrate reduction reduces gangliosides in postnatal cerebrum-brainstem and cerebellum in GM1 gangliosidosis mice (Journal of Lipid Research (April 2004) 46 (744-751))
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N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours.
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