A double-blind trial of transfer factor vs placebo in multiple sclerosis patients.
A double-blind trial of the effect of transfer factor on multiple sclerosis patients was carried out. In a series of fifty-six multiple sclerosis patients treated with monthly injections of either transfer factor or placebo for 1 year, no beneficial effect of transfer factor was noted. In addition,...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1978
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| _version_ | 1826289105750720512 |
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| author | Collins, R Espinoza, L Plank, C Ebers, G Rosenberg, R Zabriskie, J |
| author_facet | Collins, R Espinoza, L Plank, C Ebers, G Rosenberg, R Zabriskie, J |
| author_sort | Collins, R |
| collection | OXFORD |
| description | A double-blind trial of the effect of transfer factor on multiple sclerosis patients was carried out. In a series of fifty-six multiple sclerosis patients treated with monthly injections of either transfer factor or placebo for 1 year, no beneficial effect of transfer factor was noted. In addition, none of the immunological and serological parameters studied (measles migration inhibition, measles HI titre or CSF immunoglobulin) changed as a result of transfer factor therapy. Histocompatibility typing and CSF IgG/TP ratios were correlated with the disease activity. Of interest was the finding that the presence of the DW2 antigen, when unassociated with HLA-B7 antigen, appeared to correlate with the mildest form of disease activity. |
| first_indexed | 2024-03-07T02:23:50Z |
| format | Journal article |
| id | oxford-uuid:a4e658cb-f771-4f89-8ec9-7b99f7ae648f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:23:50Z |
| publishDate | 1978 |
| record_format | dspace |
| spelling | oxford-uuid:a4e658cb-f771-4f89-8ec9-7b99f7ae648f2022-03-27T02:36:50ZA double-blind trial of transfer factor vs placebo in multiple sclerosis patients.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a4e658cb-f771-4f89-8ec9-7b99f7ae648fEnglishSymplectic Elements at Oxford1978Collins, REspinoza, LPlank, CEbers, GRosenberg, RZabriskie, JA double-blind trial of the effect of transfer factor on multiple sclerosis patients was carried out. In a series of fifty-six multiple sclerosis patients treated with monthly injections of either transfer factor or placebo for 1 year, no beneficial effect of transfer factor was noted. In addition, none of the immunological and serological parameters studied (measles migration inhibition, measles HI titre or CSF immunoglobulin) changed as a result of transfer factor therapy. Histocompatibility typing and CSF IgG/TP ratios were correlated with the disease activity. Of interest was the finding that the presence of the DW2 antigen, when unassociated with HLA-B7 antigen, appeared to correlate with the mildest form of disease activity. |
| spellingShingle | Collins, R Espinoza, L Plank, C Ebers, G Rosenberg, R Zabriskie, J A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. |
| title | A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. |
| title_full | A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. |
| title_fullStr | A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. |
| title_full_unstemmed | A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. |
| title_short | A double-blind trial of transfer factor vs placebo in multiple sclerosis patients. |
| title_sort | double blind trial of transfer factor vs placebo in multiple sclerosis patients |
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