Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

OBJECTIVES: To determine whether CD8 T lymphocytes from HIV-1-infected patients expressing B*5701 and B*5703 show broad cross-reactivity against different variants of a conserved p24 epitope, which might account for the good prognosis of HIV-1-infected individuals with HLA-B*57. DESIGN: B*5701+ and...

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Autori principali: Gillespie, G, Kaul, R, Dong, T, Yang, H, Rostron, T, Bwayo, J, Kiama, P, Peto, T, Plummer, F, Mcmichael, A, Rowland-Jones, S
Natura: Journal article
Lingua:English
Pubblicazione: 2002

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