Enhancing the efficacy of viral vector blood-stage malaria vaccines

Enhancing the efficacy of viral vector blood-stage malaria vaccines

<p>Replication-deficient adenovirus (Ad) and modified vaccinia virus Ankara (MVA) vectors expressing single Plasmodium falciparum antigens can induce potent T cell and antibody responses and have entered clinical testing using a heterologous prime-boost immunisation approach (Ad_MVA). This the...

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Manylion Llyfryddiaeth
Prif Awdur:	Forbes, E
Awduron Eraill:	Hill, A
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2011
Pynciau:	Clinical laboratory sciences Malaria Immunology Vaccinology Parasitology Infectious diseases

Eitemau Tebyg

Pre-clinical development of viral vectored transmission-blocking malaria vaccines
gan: Kapulu, MC
Cyhoeddwyd: (2014)

Developing novel blood-stage malaria vaccines
gan: Douglas, AD
Cyhoeddwyd: (2015)

Malaria pre-erythrocytic stage vaccines: targeting antigen combinations
gan: Bauza, K
Cyhoeddwyd: (2012)

Towards improved blood-stage malaria vaccines: characterising the underlying immunogenicity of vaccine adjuvants and vectors
gan: de Cassan, S
Cyhoeddwyd: (2011)

Analysis of b cell responses to blood-stage malaria antigens in humans following immunization with candidate vaccines and controlled human malaria infection
gan: Elias, SC
Cyhoeddwyd: (2014)

Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches
gan: Pearson, FE
Cyhoeddwyd: (2011)

Liver-stage vaccines for malaria
gan: Longley, RJ
Cyhoeddwyd: (2013)

Long term efficacy of a pre-erythrocytic malaria vaccine and correlates of protection in children residing in a malaria endemic country
gan: Olotu, A
Cyhoeddwyd: (2013)

Hepcidin regulation in Malaria
gan: Spottiswoode, N
Cyhoeddwyd: (2015)

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C
gan: Antrobus, R
Cyhoeddwyd: (2014)

The role of antigen in the maintenance and localisation of CD8+ T-cells in the context of liver stage malaria
gan: Gola, A
Cyhoeddwyd: (2018)

Biodegradable pulsatile release technologies for viral vector based vaccinations
gan: Krastev, C
Cyhoeddwyd: (2018)

New approaches for improving the immunogenicity of modified vaccinia virus Ankara as a recombinant vaccine vector
gan: Alharbi, N
Cyhoeddwyd: (2014)

A simplified 4-site economical intradermal post-exposure rabies vaccine regimen: a randomised controlled comparison with standard methods
gan: Warrell, M, et al.
Cyhoeddwyd: (2008)

Novel adenoviral vectored vaccines and the implications of viral diversity in therapeutic strategies against Hepatitis C Virus infection
gan: Kelly, C
Cyhoeddwyd: (2013)

B cell responses to conjugate and polysaccharide meningococcal vaccines
gan: Ramasamy, M
Cyhoeddwyd: (2012)

Development of antimalarial human monoclonal antibodies against Plasmodium falciparum
gan: Wang, LT
Cyhoeddwyd: (2022)

Evaluation of the immunological mechanisms induced by mycobacteria and the potential effect this may have on immunity induced by tuberculosis vaccines
gan: Poyntz, HC
Cyhoeddwyd: (2012)

Towards the development of multi-disease vaccines against arthropod-borne viruses
gan: Montalvo Zurbía Flores, G
Cyhoeddwyd: (2022)

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
gan: Hennig, B, et al.
Cyhoeddwyd: (2008)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination
gan: Harris, S, et al.
Cyhoeddwyd: (2013)

Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
gan: Ronan, E
Cyhoeddwyd: (2011)

Evaluation of the immunogenicity of a promising vaccine regimen to identify immune correlates of protection
gan: Pinpathomrat, N
Cyhoeddwyd: (2018)

Understanding the link between interleukin 17 and vaccine-induced protection in tuberculosis
gan: Griffiths, K
Cyhoeddwyd: (2012)

CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
gan: Emilie Pollenus, et al.
Cyhoeddwyd: (2021-02-01)

Corrigendum: CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
gan: Emilie Pollenus, et al.
Cyhoeddwyd: (2022-06-01)

Control of typhoid fever: evaluating herd protection through public health use of typhoid VI polysaccharide vaccine
gan: Ochiai, R
Cyhoeddwyd: (2011)

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
gan: Matsumiya, M, et al.
Cyhoeddwyd: (2014)

Innate immune responses to tuberculosis vaccines
gan: Matsumiya, M
Cyhoeddwyd: (2014)

Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens
gan: Wong, S
Cyhoeddwyd: (2013)

T Helper Plasticity Is Orchestrated by STAT3, Bcl6, and Blimp-1 Balancing Pathology and Protection in Malaria
gan: Victor H. Carpio, et al.
Cyhoeddwyd: (2020-07-01)

Effect of needle size on immunogenicity and reactogenicity of vaccines in infants: randomised controlled trial
gan: Diggle, L, et al.
Cyhoeddwyd: (2006)

Effect of hemoglobins S and C on the in vivo expression and immune recognition of Plasmodium falciparum erythrocyte membrane protein 1 variants in Malian children
gan: Beaudry, J
Cyhoeddwyd: (2012)

Characterisation of T cells induced by candidate conserved region HIV-1 vaccines in healthy HIV-1/2 negative volunteers
gan: Ahmed, T, et al.
Cyhoeddwyd: (2014)

The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM197 conjugate vaccine
gan: Clutterbuck, E, et al.
Cyhoeddwyd: (2006)

The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection
gan: Ying Du, et al.
Cyhoeddwyd: (2020-04-01)

Comparison of a limiting dilution assay and ELISpot for detection of memory B-cells before and after immunisation with a protein-polysaccharide conjugate vaccine in children
gan: Blanchard-Rohner, G, et al.
Cyhoeddwyd: (2010)

NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment
gan: Emilie Pollenus, et al.
Cyhoeddwyd: (2024-09-01)

Discovery of a conserved Plasmodium antigen on the surface of malaria-infected red blood cells
gan: Oteng, EK
Cyhoeddwyd: (2013)

Evaluation of immune correlates to TB vaccines
gan: Marsay, L
Cyhoeddwyd: (2011)