Evidence that non-deletional mechanisms are responsible for inducing and maintaining unresponsiveness after intrathymic injection of non-professional antigen presenting cells.

INTRODUCTION: Intrathymic inoculation of donor alloantigen and concomitant immunosuppressive treatment can induce immune unresponsiveness to alloantigen. To examine the role of non-deletional mechanisms in the development of unresponsiveness, fractionated splenocytes were injected into only 1 lobe o...

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Bibliografiska uppgifter
Huvudupphovsmän: Niimi, M, Jones, N, Morris, P, Wood, K
Materialtyp: Journal article
Språk:English
Publicerad: 2000