The ABC of APC.

The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

Podrobná bibliografie
Hlavní autoři:	Fearnhead, N, Britton, M, Bodmer, W
Médium:	Journal article
Jazyk:	English
Vydáno:	2001

Podobné jednotky

Familial adenomatous polyposis (FAP) and its gene, APC.
Autor: Bodmer, W
Vydáno: (1999)

APC in the regulation of intestinal crypt fission.
Autor: Wasan, H, a další
Vydáno: (1998)

PHYSICAL MAPPING OF THE APC REGION
Autor: Thomas, H, a další
Vydáno: (1991)

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.
Autor: Cottrell, S, a další
Vydáno: (1992)

ABC of smoking cessation /
Autor: Britton, John
Vydáno: (2004)

APC mutations are sufficient for the growth of early colorectal adenomas.
Autor: Lamlum, H, a další
Vydáno: (2000)

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
Autor: Homfray, T, a další
Vydáno: (1998)

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
Autor: Fearnhead, N, a další
Vydáno: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
Autor: Fearnhead, N, a další
Vydáno: (2005)

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
Autor: Anna Höfler, a další
Vydáno: (2024-11-01)

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
Autor: Mehrnaz Ghazvini, a další
Vydáno: (2013-01-01)

APC and the three-hit hypothesis.
Autor: Segditsas, S, a další
Vydáno: (2009)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
Autor: Haines, J, a další
Vydáno: (2005)

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".
Autor: Rowan, A, a další
Vydáno: (2000)

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
Autor: Sieber, O, a další
Vydáno: (2002)

Cryo-EM structures of apo-APC/C and APC/C CDH1:EMI1 complexes provide insights into APC/C regulation
Autor: Höfler, A, a další
Vydáno: (2024)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
Autor: Lauren E. King, a další
Vydáno: (2016-03-01)

The influence of modifier genes on the disease phenotype in South African families with hereditary nonpolyposis colorectal cancer (HNPCC).
Autor: Felix, R, a další
Vydáno: (2003)

Sharing the happiness of receiving APC
Autor: Siti Nur Azwin, Zulkapri
Vydáno: (2020)

The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
Autor: Sarah Darling, a další
Vydáno: (2024-06-01)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
Autor: Coffey Robert J, a další
Vydáno: (2009-10-01)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
Autor: Lefevre, J, a další
Vydáno: (2010)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
Autor: Schneikert, Jean, a další
Vydáno: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
Autor: Jean Schneikert, a další
Vydáno: (2013-01-01)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
Autor: Stanislau Yatskevich, a další
Vydáno: (2021-03-01)

Apoptosis of the APC is concurrent with successful antigen presentation
Autor: Blancheteau, V, a další
Vydáno: (2001)

APC-Verwaltung im institutionellen Repositorium
Autor: Wagner, Alexander
Vydáno: (2018-12-01)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
Autor: Dimitriya H. Garvanska, a další
Vydáno: (2016-10-01)

Germline mutations in the mismatch repair genes hMLH1 and hMSH2 may predispose to the formation of multiple adenomatous polyps
Autor: Fearnhead, N, a další
Vydáno: (2002)

Adenomatous Polyposis Coli (APC) in cell migration
Autor: Xingyuan Fang, a další
Vydáno: (2022-06-01)

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
Autor: Harvey, J, a další
Vydáno: (2008)

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
Autor: Lamlum, H, a další
Vydáno: (2000)

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
Autor: Frayling, I, a další
Vydáno: (1998)

APC mutations dysregulate alternative polyadenylation in cancer
Autor: Austin M. Gabel, a další
Vydáno: (2024-10-01)

ABC of AIDS /
Autor: Adler, Michael W.
Vydáno: (1993)

The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
Autor: Deheragoda, MG, a další
Vydáno: (2007)

Germline epimutations of APC are not associated with inherited colorectal polyposis.
Autor: Hitchins, M, a další
Vydáno: (2006)

<it>lemmingA </it>encodes the Apc11 subunit of the APC/C in <it>Drosophila melanogaster </it>that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
Autor: Nagy Olga, a další
Vydáno: (2012-03-01)

326 warga UUM terima penghargaan APC
Autor: Utusan, Malaysia
Vydáno: (2015)

TAHNIAH SEMUA PENERIMA APC USM 2016
Autor: MPRC, Pusat Media & Perhubungan Awam
Vydáno: (2017)