The ABC of APC.

The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

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Bibliografiske detaljer
Main Authors:	Fearnhead, N, Britton, M, Bodmer, W
Format:	Journal article
Sprog:	English
Udgivet:	2001

Lignende værker

Familial adenomatous polyposis (FAP) and its gene, APC.
af: Bodmer, W
Udgivet: (1999)

APC in the regulation of intestinal crypt fission.
af: Wasan, H, et al.
Udgivet: (1998)

PHYSICAL MAPPING OF THE APC REGION
af: Thomas, H, et al.
Udgivet: (1991)

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.
af: Cottrell, S, et al.
Udgivet: (1992)

ABC of smoking cessation /
af: Britton, John
Udgivet: (2004)

APC mutations are sufficient for the growth of early colorectal adenomas.
af: Lamlum, H, et al.
Udgivet: (2000)

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
af: Homfray, T, et al.
Udgivet: (1998)

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
af: Fearnhead, N, et al.
Udgivet: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
af: Fearnhead, N, et al.
Udgivet: (2005)

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
af: Anna Höfler, et al.
Udgivet: (2024-11-01)

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
af: Mehrnaz Ghazvini, et al.
Udgivet: (2013-01-01)

APC and the three-hit hypothesis.
af: Segditsas, S, et al.
Udgivet: (2009)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
af: Haines, J, et al.
Udgivet: (2005)

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".
af: Rowan, A, et al.
Udgivet: (2000)

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
af: Sieber, O, et al.
Udgivet: (2002)

Cryo-EM structures of apo-APC/C and APC/C CDH1:EMI1 complexes provide insights into APC/C regulation
af: Höfler, A, et al.
Udgivet: (2024)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
af: Lauren E. King, et al.
Udgivet: (2016-03-01)

The influence of modifier genes on the disease phenotype in South African families with hereditary nonpolyposis colorectal cancer (HNPCC).
af: Felix, R, et al.
Udgivet: (2003)

Sharing the happiness of receiving APC
af: Siti Nur Azwin, Zulkapri
Udgivet: (2020)

The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
af: Sarah Darling, et al.
Udgivet: (2024-06-01)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
af: Coffey Robert J, et al.
Udgivet: (2009-10-01)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
af: Lefevre, J, et al.
Udgivet: (2010)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
af: Schneikert, Jean, et al.
Udgivet: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
af: Jean Schneikert, et al.
Udgivet: (2013-01-01)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
af: Stanislau Yatskevich, et al.
Udgivet: (2021-03-01)

Apoptosis of the APC is concurrent with successful antigen presentation
af: Blancheteau, V, et al.
Udgivet: (2001)

APC-Verwaltung im institutionellen Repositorium
af: Wagner, Alexander
Udgivet: (2018-12-01)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
af: Dimitriya H. Garvanska, et al.
Udgivet: (2016-10-01)

Germline mutations in the mismatch repair genes hMLH1 and hMSH2 may predispose to the formation of multiple adenomatous polyps
af: Fearnhead, N, et al.
Udgivet: (2002)

Adenomatous Polyposis Coli (APC) in cell migration
af: Xingyuan Fang, et al.
Udgivet: (2022-06-01)

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
af: Harvey, J, et al.
Udgivet: (2008)

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
af: Lamlum, H, et al.
Udgivet: (2000)

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
af: Frayling, I, et al.
Udgivet: (1998)

APC mutations dysregulate alternative polyadenylation in cancer
af: Austin M. Gabel, et al.
Udgivet: (2024-10-01)

ABC of AIDS /
af: Adler, Michael W.
Udgivet: (1993)

The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
af: Deheragoda, MG, et al.
Udgivet: (2007)

Germline epimutations of APC are not associated with inherited colorectal polyposis.
af: Hitchins, M, et al.
Udgivet: (2006)

<it>lemmingA </it>encodes the Apc11 subunit of the APC/C in <it>Drosophila melanogaster </it>that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
af: Nagy Olga, et al.
Udgivet: (2012-03-01)

326 warga UUM terima penghargaan APC
af: Utusan, Malaysia
Udgivet: (2015)

TAHNIAH SEMUA PENERIMA APC USM 2016
af: MPRC, Pusat Media & Perhubungan Awam
Udgivet: (2017)