The ABC of APC.

The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Fearnhead, N, Britton, M, Bodmer, W
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2001

Παρόμοια τεκμήρια

Familial adenomatous polyposis (FAP) and its gene, APC.
ανά: Bodmer, W
Έκδοση: (1999)

APC in the regulation of intestinal crypt fission.
ανά: Wasan, H, κ.ά.
Έκδοση: (1998)

PHYSICAL MAPPING OF THE APC REGION
ανά: Thomas, H, κ.ά.
Έκδοση: (1991)

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.
ανά: Cottrell, S, κ.ά.
Έκδοση: (1992)

ABC of smoking cessation /
ανά: Britton, John
Έκδοση: (2004)

APC mutations are sufficient for the growth of early colorectal adenomas.
ανά: Lamlum, H, κ.ά.
Έκδοση: (2000)

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
ανά: Homfray, T, κ.ά.
Έκδοση: (1998)

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
ανά: Fearnhead, N, κ.ά.
Έκδοση: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
ανά: Fearnhead, N, κ.ά.
Έκδοση: (2005)

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
ανά: Anna Höfler, κ.ά.
Έκδοση: (2024-11-01)

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
ανά: Mehrnaz Ghazvini, κ.ά.
Έκδοση: (2013-01-01)

APC and the three-hit hypothesis.
ανά: Segditsas, S, κ.ά.
Έκδοση: (2009)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
ανά: Haines, J, κ.ά.
Έκδοση: (2005)

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".
ανά: Rowan, A, κ.ά.
Έκδοση: (2000)

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
ανά: Sieber, O, κ.ά.
Έκδοση: (2002)

Cryo-EM structures of apo-APC/C and APC/C CDH1:EMI1 complexes provide insights into APC/C regulation
ανά: Höfler, A, κ.ά.
Έκδοση: (2024)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
ανά: Lauren E. King, κ.ά.
Έκδοση: (2016-03-01)

The influence of modifier genes on the disease phenotype in South African families with hereditary nonpolyposis colorectal cancer (HNPCC).
ανά: Felix, R, κ.ά.
Έκδοση: (2003)

Sharing the happiness of receiving APC
ανά: Siti Nur Azwin, Zulkapri
Έκδοση: (2020)

The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
ανά: Sarah Darling, κ.ά.
Έκδοση: (2024-06-01)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
ανά: Coffey Robert J, κ.ά.
Έκδοση: (2009-10-01)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
ανά: Lefevre, J, κ.ά.
Έκδοση: (2010)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
ανά: Schneikert, Jean, κ.ά.
Έκδοση: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
ανά: Jean Schneikert, κ.ά.
Έκδοση: (2013-01-01)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
ανά: Stanislau Yatskevich, κ.ά.
Έκδοση: (2021-03-01)

Apoptosis of the APC is concurrent with successful antigen presentation
ανά: Blancheteau, V, κ.ά.
Έκδοση: (2001)

APC-Verwaltung im institutionellen Repositorium
ανά: Wagner, Alexander
Έκδοση: (2018-12-01)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
ανά: Dimitriya H. Garvanska, κ.ά.
Έκδοση: (2016-10-01)

Germline mutations in the mismatch repair genes hMLH1 and hMSH2 may predispose to the formation of multiple adenomatous polyps
ανά: Fearnhead, N, κ.ά.
Έκδοση: (2002)

Adenomatous Polyposis Coli (APC) in cell migration
ανά: Xingyuan Fang, κ.ά.
Έκδοση: (2022-06-01)

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
ανά: Harvey, J, κ.ά.
Έκδοση: (2008)

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
ανά: Lamlum, H, κ.ά.
Έκδοση: (2000)

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
ανά: Frayling, I, κ.ά.
Έκδοση: (1998)

APC mutations dysregulate alternative polyadenylation in cancer
ανά: Austin M. Gabel, κ.ά.
Έκδοση: (2024-10-01)

ABC of AIDS /
ανά: Adler, Michael W.
Έκδοση: (1993)

The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
ανά: Deheragoda, MG, κ.ά.
Έκδοση: (2007)

Germline epimutations of APC are not associated with inherited colorectal polyposis.
ανά: Hitchins, M, κ.ά.
Έκδοση: (2006)

<it>lemmingA </it>encodes the Apc11 subunit of the APC/C in <it>Drosophila melanogaster </it>that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
ανά: Nagy Olga, κ.ά.
Έκδοση: (2012-03-01)

326 warga UUM terima penghargaan APC
ανά: Utusan, Malaysia
Έκδοση: (2015)

TAHNIAH SEMUA PENERIMA APC USM 2016
ανά: MPRC, Pusat Media & Perhubungan Awam
Έκδοση: (2017)