The ABC of APC.

The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Fearnhead, N, Britton, M, Bodmer, W
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2001

Ижил төстэй зүйлс

Familial adenomatous polyposis (FAP) and its gene, APC.
-н: Bodmer, W
Хэвлэсэн: (1999)

APC in the regulation of intestinal crypt fission.
-н: Wasan, H, зэрэг
Хэвлэсэн: (1998)

PHYSICAL MAPPING OF THE APC REGION
-н: Thomas, H, зэрэг
Хэвлэсэн: (1991)

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.
-н: Cottrell, S, зэрэг
Хэвлэсэн: (1992)

ABC of smoking cessation /
-н: Britton, John
Хэвлэсэн: (2004)

APC mutations are sufficient for the growth of early colorectal adenomas.
-н: Lamlum, H, зэрэг
Хэвлэсэн: (2000)

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
-н: Homfray, T, зэрэг
Хэвлэсэн: (1998)

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
-н: Fearnhead, N, зэрэг
Хэвлэсэн: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
-н: Fearnhead, N, зэрэг
Хэвлэсэн: (2005)

Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation
-н: Anna Höfler, зэрэг
Хэвлэсэн: (2024-11-01)

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.
-н: Mehrnaz Ghazvini, зэрэг
Хэвлэсэн: (2013-01-01)

APC and the three-hit hypothesis.
-н: Segditsas, S, зэрэг
Хэвлэсэн: (2009)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
-н: Haines, J, зэрэг
Хэвлэсэн: (2005)

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".
-н: Rowan, A, зэрэг
Хэвлэсэн: (2000)

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
-н: Sieber, O, зэрэг
Хэвлэсэн: (2002)

Cryo-EM structures of apo-APC/C and APC/C CDH1:EMI1 complexes provide insights into APC/C regulation
-н: Höfler, A, зэрэг
Хэвлэсэн: (2024)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
-н: Lauren E. King, зэрэг
Хэвлэсэн: (2016-03-01)

The influence of modifier genes on the disease phenotype in South African families with hereditary nonpolyposis colorectal cancer (HNPCC).
-н: Felix, R, зэрэг
Хэвлэсэн: (2003)

Sharing the happiness of receiving APC
-н: Siti Nur Azwin, Zulkapri
Хэвлэсэн: (2020)

The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation
-н: Sarah Darling, зэрэг
Хэвлэсэн: (2024-06-01)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
-н: Coffey Robert J, зэрэг
Хэвлэсэн: (2009-10-01)

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
-н: Lefevre, J, зэрэг
Хэвлэсэн: (2010)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
-н: Schneikert, Jean, зэрэг
Хэвлэсэн: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
-н: Jean Schneikert, зэрэг
Хэвлэсэн: (2013-01-01)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
-н: Stanislau Yatskevich, зэрэг
Хэвлэсэн: (2021-03-01)

Apoptosis of the APC is concurrent with successful antigen presentation
-н: Blancheteau, V, зэрэг
Хэвлэсэн: (2001)

APC-Verwaltung im institutionellen Repositorium
-н: Wagner, Alexander
Хэвлэсэн: (2018-12-01)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
-н: Dimitriya H. Garvanska, зэрэг
Хэвлэсэн: (2016-10-01)

Germline mutations in the mismatch repair genes hMLH1 and hMSH2 may predispose to the formation of multiple adenomatous polyps
-н: Fearnhead, N, зэрэг
Хэвлэсэн: (2002)

Adenomatous Polyposis Coli (APC) in cell migration
-н: Xingyuan Fang, зэрэг
Хэвлэсэн: (2022-06-01)

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.
-н: Harvey, J, зэрэг
Хэвлэсэн: (2008)

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
-н: Lamlum, H, зэрэг
Хэвлэсэн: (2000)

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
-н: Frayling, I, зэрэг
Хэвлэсэн: (1998)

APC mutations dysregulate alternative polyadenylation in cancer
-н: Austin M. Gabel, зэрэг
Хэвлэсэн: (2024-10-01)

ABC of AIDS /
-н: Adler, Michael W.
Хэвлэсэн: (1993)

The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
-н: Deheragoda, MG, зэрэг
Хэвлэсэн: (2007)

Germline epimutations of APC are not associated with inherited colorectal polyposis.
-н: Hitchins, M, зэрэг
Хэвлэсэн: (2006)

<it>lemmingA </it>encodes the Apc11 subunit of the APC/C in <it>Drosophila melanogaster </it>that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
-н: Nagy Olga, зэрэг
Хэвлэсэн: (2012-03-01)

326 warga UUM terima penghargaan APC
-н: Utusan, Malaysia
Хэвлэсэн: (2015)

TAHNIAH SEMUA PENERIMA APC USM 2016
-н: MPRC, Pusat Media & Perhubungan Awam
Хэвлэсэн: (2017)