The ABC of APC.

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of adenomatous polyps in the colon and rectum, with inevitable development of colorectal cancer if left untreated. FAP is caused by germline mutations in the adenomatous polyposis coli (APC)...

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Autori principali: Fearnhead, N, Britton, M, Bodmer, W
Natura: Journal article
Lingua:English
Pubblicazione: 2001