Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels.
We carried out a genome-wide association study of hemoglobin levels in 16,001 individuals of European and Indian Asian ancestry. The most closely associated SNP (rs855791) results in nonsynonymous (V736A) change in the serine protease domain of TMPRSS6 and a blood hemoglobin concentration 0.13 (95%...
Main Authors: | Chambers, J, Zhang, W, Li, Y, Sehmi, J, Wass, M, Zabaneh, D, Hoggart, C, Bayele, H, McCarthy, M, Peltonen, L, Freimer, N, Srai, S, Maxwell, P, Sternberg, M, Ruokonen, A, Abecasis, G, Jarvelin, MR, Scott, J, Elliott, P, Kooner, J |
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Format: | Journal article |
Language: | English |
Published: |
2009
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