Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis.

Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis.

OBJECTIVE: To determine the influence of HLA-B27 homozygosity and HLA-DRB1 alleles in the susceptibility to, and severity of, ankylosing spondylitis in a Finnish population. METHODS: 673 individuals from 261 families with ankylosing spondylitis were genotyped for HLA-DRB1 alleles and HLA-B27 hetero...

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Bibliographic Details
Main Authors:	Jaakkola, E, Herzberg, I, Laiho, K, Barnardo, M, Pointon, J, Kauppi, M, Kaarela, K, Tuomilehto-Wolf, E, Tuomilehto, J, Wordsworth, B, Brown, M
Format:	Journal article
Language:	English
Published:	2006

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