Accurate Computation of Likelihoods in the Coalescent with Recombination via Parsimony.
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of applications. A widely-used method of estimating recombination rates is the maximum likelihood approach, and the problem of...
Main Authors: | Lyngsø, R, Song, Y, Hein, J |
---|---|
格式: | Journal article |
語言: | English |
出版: |
2008
|
相似書籍
-
On recombination-induced multiple and simultaneous coalescent events.
由: Davies, J, et al.
出版: (2007) -
Parsimonious reconstruction of sequence evolution and haplotype blocks: Finding the minimum number of recombination events
由: Song, Y, et al.
出版: (2003) -
Most parsimonious reconciliation in the presence of gene duplication, loss, and deep coalescence using labeled coalescent trees
由: Wu, Yi-Chieh, et al.
出版: (2014) -
Minimum recombination histories by branch and bound
由: Lyngso, R, et al.
出版: (2005) -
Approximating the coalescent with recombination.
由: Mcvean, G, et al.
出版: (2005)