Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest.

Catechol-O-methyltransferase (COMT) modulates dopamine in the prefrontal cortex (PFC) and influences PFC dopamine-dependent cognitive task performance. A human COMT polymorphism (Val(158)Met) alters enzyme activity and is associated with both the activation and functional connectivity of the PFC dur...

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Bibliographic Details
Main Authors: Tunbridge, E, Farrell, S, Harrison, P, Mackay, C
Format: Journal article
Language:English
Published: 2013