Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.
We have examined the role of the human CD59 antigen in inhibiting complement-mediated lysis by transfer and expression of a CD59 cDNA in rat cells. A cDNA encoding CD59 was subcloned into the expression vector pSFSVneo and stably transfected into the rat T cell line NB2-6TG. Indirect immunofluoresce...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1991
|